When Manda proves too elusive for Katsuyu and Gamabunta, Tsunade uses Gamabunta's sword to pin Manda to the ground with his mouth shut. She, Jiraiya, and Orochimaru each summon Katsuyu, Gamabunta, and Manda, respectively.

Her resolve to protect Naruto eventually overcomes her fear of blood, allowing her to go on the offensive: she kicks Orochimaru, activates Creation Rebirth to heal all the damage she's received, and declares her acceptance of the position of Fifth Hokage. Orochimaru keeps trying to attack him, which Tsunade keeps using her body to block. Tsunade uses her body to block the attack, her way of protecting Naruto, Konoha's future Hokage. Orochimaru decides to kill Naruto and attacks with his Sword of Kusanagi. She succeeds, and in a brief moment of regained consciousnesses Naruto claims the necklace he's won. Tsunade tries healing him, fearing that he'll die just like Nawaki and Dan did. Kabuto is defeated, but as his last act he severs Naruto's heart muscles. Naruto persists and, after making a shadow clone to help him, he is able to strike Kabuto with a perfected Rasengan. Naruto stops him and attacks with an incomplete Rasengan, but misses, causing Kabuto to start commenting on his lack of talent, just as Tsunade did the week before. Kabuto approaches Tsunade and tries to restrain her, which she is unable to fend off in her condition. Naruto is quickly defeated by Kabuto, as is Shizune when she tries to face him afterwards. Shizune looks after Tsunade as she shudders from the blood while Jiraiya fights Orochimaru and Naruto fights Kabuto. Jiraiya, Shizune, and Naruto eventually arrive to help. Unable to stop her through conventional means, Kabuto slits his own wrists and coats her with his blood, paralysing her due to her phobia. They draw her away from the city and Kabuto, a medic-nin, tries neutralising her, but she heals all the debilitating damage he does. Orochimaru and Kabuto state that they'll force her to heal his arms, causing her to attack them. Although she desperately wants to see Nawaki and Dan again, she knows they wouldn't want to be brought back at the cost of Konoha's safety, something Naruto has reminded her of. Orochimaru questions why she would deceive him, to which she replies that she knew he was lying about sparing Konoha. She approaches him, apparently to heal him, but Kabuto notices at the last moment that she has killing intent and stops her. Tsunade meets with Orochimaru and agrees to heal his arms on the condition that he would leave Konoha alone. ► Naruto, Jiraiya and Tsunade vs Orochimaru and Kabuto at: Title: Naruto, Jiraiya and Tsunade vs Orochimaru and Kabuto

Naruto and tsunade sub indo